GrantTANGO2 Research FoundationAccepting applications

TANGO2 Research Foundation Cycle 7 Grants: Up to $50,000 for Rare Disease Researchers in the US and Abroad

The TANGO2 Research Foundation has opened Cycle 7 of its research grants, funding seed and pilot projects at up to $25,000 for a single institution and up to $50,000 for multi institution work. The call is open to U.
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About this opportunity

The TANGO2 Research Foundation funds research into TANGO2 deficiency disorder, a rare genetic condition that affects how cells handle energy, and it runs its grants in numbered cycles. Cycle 7 is built for seed and pilot work: projects that test whether an idea is feasible, refine a method and set up a larger study later. It is the kind of funding that exists to get a difficult first step done rather than to keep a finished machine running.

Two categories are available. A single institution grant supports a research initiative within one institution for up to $25,000, while a multi institution grant supports collaborating sites for up to $50,000, with an opportunity for additional funding through a competitive one year renewal. The award period is one year, starting July 1, 2027.

The call is explicitly open to U.S. and international researchers, which means a researcher attached to an African university hospital or research institute can apply. You need a terminal degree, MD, DO, PhD, NP or an international equivalent, and you should be working in an academic medical institution or a non profit or research institution. Postdoctoral researchers can apply if they provide a letter of employment verifying they will begin a faculty position at, or equivalent to, assistant professor level by the start of the funding period in Fall 2027.

Plan for a two step process. The first

Application timeline

is the Letter of Intent, due at 5:00 pm EST on November 6, 2026, with status notifications on December 4, 2026. Full proposals are invited only, and the invited

Application timeline

is February 26, 2027, with award notifications in May or June 2027. That structure rewards a sharp, honest Letter of Intent, since it decides whether you get to the second round at all.

What you receive

  • Up to $25,000 for a single institution research project
  • Up to $50,000 for a multi institution research project
  • Opportunity for additional funding through a competitive one year renewal
  • A one year award period starting July 1, 2027
  • Funding aimed at seed and pilot work, testing feasibility and refining methodologies before a larger study

Who can apply

  • A clinical, basic or community researcher with a terminal degree, MD, DO, PhD, NP or an international equivalent
  • Working in an academic medical institution or a non profit or research institution
  • Open to U.S. and international researchers
  • Postdoctoral applicants must provide a letter of employment verifying a faculty position at, or equivalent to, assistant professor level by the start of the funding period in Fall 2027
  • The applicant submits through the foundation's Submittable portal, starting with a Letter of Intent

Who should not apply

  • The full proposal stage is by invitation only, so applicants whose Letter of Intent is not advanced cannot submit a full proposal in this cycle

Documents to prepare

  • A Letter of Intent completed in the foundation's Submittable portal
  • The Letter of Intent Details document from the grants page, used to prepare the submission
  • A letter of employment for postdoctoral applicants who will start a faculty position in Fall 2027
  • A full proposal package, prepared only after an invitation follows the Letter of Intent decision

How to apply

  • Read the Cycle 7 grant description and download the Letter of Intent Details document from the TANGO2 Research Foundation grants page
  • Open the Cycle 7 Letter of Intent form in the foundation's Submittable portal and create an account if you do not have one
  • Write a Letter of Intent that makes the feasibility case for a seed or pilot project, naming the institution or institutions involved
  • Submit the Letter of Intent by 5:00 pm EST on November 6, 2026
  • Watch for the Letter of Intent status notification on December 4, 2026 at 5:00 pm EST
  • If invited, submit the full proposal by 5:00 pm EST on February 26, 2027

Selection process

  • Letters of Intent are reviewed first, and status notifications go out on December 4, 2026 at 5:00 pm EST
  • Only invited applicants move to the full proposal stage, due February 26, 2027
  • Notification of awards is made in May or June 2027
  • The award start date is July 1, 2027 for a one year project period

Sources and verification

Related opportunities

Questions applicants ask

Is this open to researchers outside the United States?

Yes. The foundation lists U.S. and international researchers as eligible, provided the applicant holds a terminal degree and works in an academic medical institution or a non profit or research institution.

What is the difference between the two grant categories?

A single institution grant supports a research initiative within one institution for up to $25,000. A multi institution grant supports collaborating institutions for up to $50,000, with the chance of a competitive one year renewal.

Can I send a full proposal straight away?

No. The full proposal stage is by invitation only and follows the Letter of Intent decision on December 4, 2026.

Do postdoctoral researchers qualify?

Yes, if they provide a letter of employment verifying they will begin a faculty position at, or equivalent to, assistant professor level by the beginning of the funding period in Fall 2027.

When does the funding start?

Awards are notified in May or June 2027 and the award start date is July 1, 2027 for a one year period.

Important disclaimer

Nextali researches and curates useful opportunities to make discovery easier. Before applying, verify every timeline, requirement, fee and application link on the official provider website. Do your own research into the organisation, its background and the authenticity of the offer. Nextali does not guarantee selection, funding or the conduct of third party providers.

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